MersV1, Main, Exploration, bibRecord, 001269

Estimating the Severity and Subclinical Burden of Middle East Respiratory Syndrome Coronavirus Infection in the Kingdom of Saudi Arabia.

Identifieur interne : 001269 ( Main/Exploration ); précédent : 001268; suivant : 001270

Estimating the Severity and Subclinical Burden of Middle East Respiratory Syndrome Coronavirus Infection in the Kingdom of Saudi Arabia.

Auteurs : Justin Lessler ; Henrik Salje ; Maria D. Van Kerkhove ; Neil M. Ferguson ; Simon Cauchemez ; Isabel Rodriquez-Barraquer ; Rafat Hakeem ; Thibaut Jombart ; Ricardo Aguas ; Ali Al-Barrak ; Derek A T. Cummings

Source :

American journal of epidemiology [ 1476-6256 ] ; 2016.

RBID : pubmed:26851269

Descripteurs français

KwdFr :
- Adolescent, Adulte, Adulte d'âge moyen, Arabie saoudite (épidémiologie), Coronavirus du syndrome respiratoire du Moyen-Orient, Enfant, Enfant d'âge préscolaire, Humains, Infections asymptomatiques (épidémiologie), Infections à coronavirus (épidémiologie), Jeune adulte, Nourrisson, Sujet âgé.
MESH :
- épidémiologie : Arabie saoudite, Infections asymptomatiques, Infections à coronavirus.
- Adolescent, Adulte, Adulte d'âge moyen, Coronavirus du syndrome respiratoire du Moyen-Orient, Enfant, Enfant d'âge préscolaire, Humains, Jeune adulte, Nourrisson, Sujet âgé.
Wicri :
- geographic : Arabie saoudite.

English descriptors

KwdEn :
- Adolescent, Adult, Aged, Asymptomatic Infections (epidemiology), Child, Child, Preschool, Coronavirus Infections (epidemiology), Humans, Infant, Middle Aged, Middle East Respiratory Syndrome Coronavirus, Saudi Arabia (epidemiology), Young Adult.
MESH :
- geographic , epidemiology : Saudi Arabia.
- epidemiology : Asymptomatic Infections, Coronavirus Infections.
- Adolescent, Adult, Aged, Child, Child, Preschool, Humans, Infant, Middle Aged, Middle East Respiratory Syndrome Coronavirus, Young Adult.

Abstract

Not all persons infected with Middle East respiratory syndrome coronavirus (MERS-CoV) develop severe symptoms, which likely leads to an underestimation of the number of people infected and an overestimation of the severity. To estimate the number of MERS-CoV infections that have occurred in the Kingdom of Saudi Arabia, we applied a statistical model to a line list describing 721 MERS-CoV infections detected between June 7, 2012, and July 25, 2014. We estimated that 1,528 (95% confidence interval (CI): 1,327, 1,883) MERS-CoV infections occurred in this interval, which is 2.1 (95% CI: 1.8, 2.6) times the number reported. The probability of developing symptoms ranged from 11% (95% CI: 4, 25) in persons under 10 years of age to 88% (95% CI: 72, 97) in those 70 years of age or older. An estimated 22% (95% CI: 18, 25) of those infected with MERS-CoV died. MERS-CoV is deadly, but this work shows that its clinical severity differs markedly between groups and that many cases likely go undiagnosed.

DOI: 10.1093/aje/kwv452
PubMed: 26851269

Affiliations:

Le document en format XML

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<front><div type="abstract" xml:lang="en">Not all persons infected with Middle East respiratory syndrome coronavirus (MERS-CoV) develop severe symptoms, which likely leads to an underestimation of the number of people infected and an overestimation of the severity. To estimate the number of MERS-CoV infections that have occurred in the Kingdom of Saudi Arabia, we applied a statistical model to a line list describing 721 MERS-CoV infections detected between June 7, 2012, and July 25, 2014. We estimated that 1,528 (95% confidence interval (CI): 1,327, 1,883) MERS-CoV infections occurred in this interval, which is 2.1 (95% CI: 1.8, 2.6) times the number reported. The probability of developing symptoms ranged from 11% (95% CI: 4, 25) in persons under 10 years of age to 88% (95% CI: 72, 97) in those 70 years of age or older. An estimated 22% (95% CI: 18, 25) of those infected with MERS-CoV died. MERS-CoV is deadly, but this work shows that its clinical severity differs markedly between groups and that many cases likely go undiagnosed. </div>
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Serveur d'exploration MERS

Estimating the Severity and Subclinical Burden of Middle East Respiratory Syndrome Coronavirus Infection in the Kingdom of Saudi Arabia.

Estimating the Severity and Subclinical Burden of Middle East Respiratory Syndrome Coronavirus Infection in the Kingdom of Saudi Arabia.

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki

	Serveur d'exploration MERS
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